A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived

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The alarm comes from changes in the way taxpayers’ money is invested by UK Research and Innovation (UKRI), which recently published its plan on how to disburse £38.6bn of public research and development funding over the next four years. Change is always unsettling, and as the UKRI’s chief executive, Ian Chapman, says, there will always be those who lose out when change happens. Difficult choices must be made.